* Auto End Points for pore computation: 4
* Inside Points for TM-pore computation: 8
* Outside Points for TM-pore computation: 1
* Transmembrane Classification: OPM
Comment: The functionally significant channel we are interested in this struacture can be automatically found by extracting channels between top ranked boundary points inside and outside the membrane. However, as can be easily observed this structure has three barrel like subunits, so we set inside points to 8 to ensure we find channels through all subunits.
Unfortunately, trans-membrane pores method fails to find the correct pore through one of the subunits even after setting inside points to 8. However, ignoring trans-membrane classification information and finding pores between 4 most important boundary points allows identification of pores through all subunits.How to view: Rank 1, 2 and 4 pores in "Trans-membrane Pores" table are interesting, while Rank 1, 3 and 5 pores in "Pores" table are interesting.
Click on any table row below to view the corresponding channel.
|Rank||Pt 1||Pt 2||Length||Bottle-neck||Straightness||Score|
|Rank||Out Pt||In Pt||Length||Bottle-neck||Straightness||Score|